If you take a medicine like this to help you sleep, be aware of the pain reliever in the pill.
Some people want an analgesic mixed in with their antihistimine, but if you do not, look for antihistimine sleep aids with no pain reliever. Brain signals needed to keep us awake include histaminergic signals.
Topical antihistamine products are where antihistamines have been incorporated in creams, nasal sprays and other agents that can be applied locally (for example to the skin) to treat allergic reactions.
Topical antihistamines are used to relieve the symptoms of hay fever, itching and to resolve rashes due to allergy.
A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition.
Antihistamines are often the first sleep medication insomniacs take, and they are often sufficient. The regulatory authorities have decided they are safe enough that responsible adults can use them unsupervised.
Like all sleep medications, antihistamines artificially modify a person's sleep patterns.
During an allergic reaction, action at the histamine receptor sites causes a multitude of body responses.
Antihistamines compete for the histamine receptor sites (most commonly H1-receptor sites) in order to block histamine, thus stopping or lessening the allergic reaction.
Somaxon Pharamaceuticals introduced the old tricyclic antidepressant drug doxepin under the brand name Silenor in 2011.
In addition to effects on serotonin and norepinephrine, doxepin appears to have anti-histamine properties.
There is also the possibility of drug resistance where the body adapts to the antihistimine and it doesn't work as well.
And like other hypnotics, the long-term effectiveness of antihistamines has not been demonstrated in a manner that would satisfy scientists.
The H-1 antihistamines block those signals and make us sleepy.